23rd September 1910
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Dr Hawley Harvey Crippen had been arrested in Canada on the 31st July 1910 and was being held in London awaiting his trial for the murder of his wife, Cora, which was to start on the 18th October. The prosecution team was actually led by Mr Muir, not Sir Rufus Isaacs, assisted by Mr Humphreys and a Mr Oddie. Defence council was led by Mr Tobin KC. Crippen was found guilty and hanged.
If you are really interested you can read the whole trial proceedings in this 1919 book by Filson Young online and free here.